Answer 90 - Tropical disease drug treatments
The following conditions and drug treatments are correctly paired:
True a. onchocerciasis: ivermectin
True b. schistosomiasis: praziquantel
False c. visceral leishmaniasis: suramin
False d. Rhodesian trypanosomiasis: pentavalent antimony
True e. hydatid disease: albendazole
Table 90
| Drug treatments of some major tropical diseases |
| Infection |
First line treatment |
Second line treatment |
| onchocerciasis |
ivermectin |
suramin
DEC |
| schistosomiasis |
praziquantal (for all species) |
metrifonate (S.haemotobium)
oxamniquine (S.mansoni) |
| visceral leishmaniasis |
sodium stibogluconate |
amphotericin B pentamidine
allopurinol |
| Rhodesian trypanosomiasis |
suramin |
melarsoprol (if CNS involved) |
| Gambian trypanosomiasis |
suramin or pentamidine |
melarsoprol or eflornithine (if CNS involved) |
| hydatid disease |
albendazole |
praziquantal |
