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MCQs in Tropical Medicine

Rob Skelly DTM+H FRCP

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Answer 90 - Tropical disease drug treatments

The following conditions and drug treatments are correctly paired:
True a. onchocerciasis: ivermectin
True b. schistosomiasis: praziquantel

False c. visceral leishmaniasis: suramin
False d. Rhodesian trypanosomiasis: pentavalent antimony
True e. hydatid disease: albendazole

Table 90

Drug treatments of some major tropical diseases
Infection First line treatment Second line treatment
onchocerciasis ivermectin suramin
schistosomiasis praziquantal (for all species) metrifonate (S.haemotobium)
oxamniquine (S.mansoni)
visceral leishmaniasis sodium stibogluconate amphotericin B pentamidine
Rhodesian trypanosomiasis suramin melarsoprol (if CNS involved)
Gambian trypanosomiasis suramin or pentamidine melarsoprol or eflornithine (if CNS involved)
hydatid disease albendazole praziquantal

Copyright: Rob Skelly 2006